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Xpert® Xpress Flu

Flu computer generated depiction.
Qualitative detection and differentiation of influenza A and influenza B

The Need

an ill woman listens to a physician
  • Respiratory viruses, especially influenza, mutate rapidly and novel strains can emerge with little notice.
  • Sensitivities of Rapid EIA Flu tests range from 50-70%1
  • This genetic evolution can potentially impact the performance of molecular diagnostic tests if mutations occur within the test’s targeted regions.2
(1) CDC. Information for Clinicians on Rapid Diagnostic Testing for Influenza. https://www.cdc.gov/flu/professionals/diagnosis/rapidclin.htm#:~:text=Sensitivities%20of%20rapid%20 influenza%20diagnostic%20tests%20are%20low,culture%20or%20reverse%20transcription%20polymerase%20chain%20reaction%20%28RT-PCR%29. Accessed June 2023.
(2) Jørgensen RL, Lerche CJ, Pedersen MS, Kirkby NS, Botnen AB, Trebbien R, Nilsson-Møller S, Pinholt M,Nielsen ACY, Westh H, Lisby JG, Schneider UV. Emergence of circulating influenza A H3N2 viruses with genetic drift in the matrix gene: be alert of false-negative test results. APMIS. 2022; 130: 612–617.

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