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Xpert® Xpress MVP

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Xpert® Xpress MVP (10-test kit)

XPRSMVP-10

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Collection devices

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Swab Specimen Collection Kit (Pack of 50)

SWAB/G-50-US

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Xpert CT/NG

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90-minute detection and differentiation of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG)

FAQs

1. What does the Xpert Xpress MVP test for?

1. What does the Xpert Xpress MVP test for?

Performed on the GeneXpert® system, Xpert Xpress MVP is an automated qualitative in vitro diagnostic test for the detection of DNA targets from anaerobic bacteria associated with bacterial vaginosis (BV), Candida species associated with vulvovaginal candidiasis (VVC), and Trichomonas vaginalis (TV). (1)

2. What type of specimens does the Xpert Xpress MVP test use?

2. What type of specimens does the Xpert Xpress MVP test use?

Xpert Xpress MVP test uses clinician-collected and self-collected vaginal swabs (collected in a clinical setting) from patients who are symptomatic for vaginitis/vaginosis.(1)  

3. How does the Xpert Xpress MVP test work?

3. How does the Xpert Xpress MVP test work?

Xpert Xpress MVP test utilizes real-time polymerase chain reaction (PCR) for the amplification of specific DNA targets and utilizes fluorogenic target-specific hybridization probes to detect and differentiate DNA from anaerobic organisms associated with bacterial vaginosis (BV), Candida species associated with vulvovaginal candidiasis (VVC) and Trichomonas vaginalis (TV). (1)

4. What infections are the Xpert Xpress MVP tests intended to aid in the diagnosis?

4. What infections are the Xpert Xpress MVP tests intended to aid in the diagnosis?

The Xpert Xpress MVP test is intended to aid in the diagnosis of vaginal infections in women with a clinical presentation consistent with BV, VVC, or TV. (1)

5. Are co-infections common across bacterial vaginosis, vulvovaginal candidiasis, or trichomoniasis?

5. Are co-infections common across bacterial vaginosis, vulvovaginal candidiasis, or trichomoniasis?

“Yes. Co‑infections are common. In a multicenter clinical study, mixed infections were identified in 17.9% of women with vaginitis/vaginosis symptoms, with the most prevalent combination being bacterial vaginosis and Candida species (~11%). (2)"

6. Can you use the same collection kit as the Xpert® CT/NG test?

6. Can you use the same collection kit as the Xpert® CT/NG test?

Yes, both Xpert Xpress MVP and Xpert CT/NG use SWAB/G-50-US.

References:
 

1. Cepheid. Xpert Xpress MVP Package Insert. Accessed Dec. 18, 2023. https://www.cepheid.com/en-USntent/dam/www-cepheid-com/documents/package-insert-files/Xpert%20Xpress%20MVP%20US-IVD%20ENGLISH%20Instructions%20for%20Use%20301-8994%2c%20Rev%20E.pdf

2. Lillis RA, Parker RL, Ackerman R, et al. Clinical Evaluation of a New Molecular Test for the Detection of Organisms Causing Vaginitis and Vaginosis. J Clin Microbiol. 2023;61(3):e0174822. doi:10.1128/jcm.01748-22.