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Xpert® Xpress GBS

GBS computer generated depiction.
Qualitative real-time PCR test providing accurate intrapartum detection of Group B Streptococcus in labor/delivery

The Need

an ill woman listens to a physician
Group B Streptococcus (GBS) remains a leading cause of early-onset neonatal sepsis. Rates of maternal colonization have not changed, but universal antenatal screening at 35–37 weeks along with the use of intrapartum antibiotic prophylaxis (IAP) has resulted in a decrease of early-onset disease.1
Challenges remain, including:
  • The latest ACOG practice guidelines recommend universal antepartum screening along with intrapartum where indicated based on risk.
  • GBS colonization can be transient 2 and identifying women colonized at the time of delivery can be challenging.
  • Some women present at the delivery room with unknown GBS status.
1 ASM, March 2020, Guidelines for the Detection and Identification of Group B Streptococcus - Revised Guidelines from CDC, 2020.
2 ACOG Committee Opinion No. 797: Prevention of Group B Streptococcal Early-Onset Disease in Newborns. Obstet Gynecol. 2020 Feb;135(2):e51-e72.

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