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December 09, 2025
EXPERT SPOTLIGHT
Article
Expert Spotlight: Michael Loeffelholz Ph.D., Vice President of Scientific Affairs
As we highlight the work of Michael Loeffelholz, Ph.D., Vice President of Scientific Affairs, we’re reminded of the depth of clinical microbiology expertise, diagnostic innovation, and leadership he brings to Cepheid.
Dr. Loeffelholz earned his Ph.D. from Ohio University and completed a postdoctoral fellowship at the University of Rochester. His career spans leadership roles in public health and reference labs, a tenured professorship and medical directorship at University of Texas Medical Branch, and key advisory positions with the U.S. Centers for Disease Control and Prevention (CDC) and Clinical and Laboratory Standards Institute (CLSI).
Since joining Cepheid in 2018, Dr. Loeffelholz has played a pivotal role in shaping diagnostic strategy, advancing infectious disease testing, and mentoring the next generation of scientific leaders. With over 100 publications, his thoughtful approach and dedication to quality continue to drive progress in infectious disease testing and elevate the standards of diagnostic science.
Dr. Loeffelholz was awarded the 2026 American Society for Microbiology (ASM) Award for Service. This prestigious award honors individuals who have demonstrated exceptional service, dedication, and leadership within ASM and have made lasting contributions to the field of microbiology. For Dr. Loeffelholz, this recognition carries profound personal meaning as he reflects on his career spanning over four decades.
Dr. Loeffelholz shares the following insights on his notable career journey with Cepheid thus far:
Why did you choose to join Cepheid?
I have known Dr. Dave Persing (Cepheid’s former Chief Medical & Scientific Officer) for over 25 years. I was excited about the opportunity to work alongside Dr. Persing to cement Cepheid’s market leadership position, thereby multiplying the positive impact on patient lives.
What notable contributions have you made to Cepheid?
I was part of the teams that developed Cepheid’s Xpert® Xpress SARS-CoV-2 test, which received FDA Emergency Use Authorization. Leveraging our global GeneXpert® network, we delivered over 100 million tests to help slow the spread of COVID-19. I’ve also mentored and led teams, helping to shape the next generation of leaders. My work continues to focus on designing robust, multi-target diagnostic tests that can detect emerging viral variants and support clinicians in making timely, accurate decisions.
What past educational, research, or professional experience are you most proud of?
I am board certified by the American Board of Medical Microbiology (ABMM). I am most proud of my time spent training and mentoring the next generation of leaders in the field of infectious disease microbiology.
What inspires you outside of work?
I find daily inspiration in my family—my wife, children, and grandchild—whose love and support continue to motivate me beyond the workplace.
Learn more about Dr. Loeffelholz’s professional expertise on LinkedIn.
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