Xpert SA Nasal Complete

Xpert® SA Nasal Complete

Pre-surgical Testing of S. aureus and MRSA in About an Hour

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  • The Need

    Staphylococcus aureus infections are an increasingly serious public health issue

    Colonized patients at risk for serious complications include surgical, trauma, burn and dialysis patients:

    • S. aureus colonized patients are up to 9 times more likely to develop surgical site infections than non-carriers1
    • S. aureus is the major cause of access infections and bacteremia in dialysis patients2
    • Carriage is the major risk factor for infection with S. aureus in dialysis patients4
    • Up to 93% of nosocomial S. aureus infections are caused by a patient’s own flora3,4
    • SA and MRSA infections are associated with increases in length of hospital stay, costs, morbidity, and mortality6,7,11
    • Nasal carriage of S. aureus and self-infection of wounds in ICU/Burn patients is well documented9,10

    (1) Kluytmans, J., Clinical Microbiology Review, 1997, Vol 10, No. 3; (2) Piraino, B., Staphylococcus aureus Infections in Dialysis Patients: Focus on Prevention, ASAIO Journal 2000; 46:S13-S17; (3) Critchley et al, Drug Discovery Today, 2006, Vol. 3 No. 2; (4) VL Yu et al., “Staphylococcus aureus nasal carriage and infection in patients on hemodialysis. Efficacy of antibiotic prophylaxis.” NEJM July 1986; (5) Murphy D., et al. “Dispelling the Myths: The True Cost of Healthcare-Associated Infections. An APIC Briefing”, February 2007.; (6) Engemann et al. “Adverse clinical and economic outcomes attributable to methicillin resistance among patients with Staphylococcus aureus surgical site infection, CID 36;2003; (7) Anderson et al. “Clinical and Financial Outcomes Due to Methicillin Resistant Staphylococcus aureus Surgical Site Infection: A Multi-Center Matched Outcomes Study”, PLoS One; 2009; (8) Bode et al, “Preventing Surgical-Site Infections in Nasal Carriers of Staphylococcus aureus”, NEJM January 2010; (9) Mackie et al, “Reduction in Staphylococcus aureus wound colonization ...”, Burns 1994; 20, (1), S14-S18; (10) Kooistra-Smid et al, “Molecular epidemiology of Staphylococcus aureus colonization in a burn center”, Burns 2004, Feb; 30. 1:27-33; (11) Noskin et al, “The Burden of Staphylococcus aureus Infections on Hospitals in the United States”, Arch Intern Medicine Vol 165, Aug 2005

    The Solution

    Rapid and accurate detection of colonization facilitates targeted infection control practices:

    • Optimize pre-admission workflow and counseling
    • Enables measures to reduce endogenous infection risk, including decolonization
    • Supports measures to reduced exogenous infection risk, including barrier/contact precautions
    • Aligns with infection control strategies as outlined by SCIP and SHEA/IDSA
    • Cepheid - Our Vision for a Better Way
    • Catalog #:

      Xpert SA Nasal Complete
      Number of Tests: 10