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Test Information
Home / Tests / Oncology/Genetics / Xpert NPM1 Mutation

Xpert® NPM1 Mutation  

Quantitative assay of the NPM1 mRNA transcripts (Type A, B, and D) and the ABL1 endogenous control mRNA transcript in EDTA peripheral blood samples. For Research Use Only (RUO). Not for use in diagnostic procedures.

Xpert<sup>®</sup>&nbsp;NPM1 Mutation
&nbsp;

The Need


Current testing options for NPM1 are not only cumbersome, but also expensive and time consuming for the lab to implement because:

  • Available testing methods are complex and create inefficient laboratory workflows.
  • No international scale has been established for NPM1 monitoring, so laboratories are dependent on ratios and must run laborious standard curves.

The Solution


Leveraging Cepheid’s lab in a cartridge™ technology, the Xpert NPM1 Mutation assay decreases workflow complexity and hands-on time by automating the entire testing process, delivering faster results.

The Xpert NPM1 Mutation assay is a quantitative assay for the NPM1 mutation transcripts (types A, B and D in exon 12) as a ratio of NPM1 Mutation/ABL1. It provides high assay sensitivity, standardization, and on-demand molecular results in about 2.5 hours. With minimal hands-on time and a streamlined
workflow, the Xpert NPM1 Mutation assay eliminates the need for time consuming hands-on processes and enables researchers to run NPM1 testing in-house.

Easy to Use

  • < 2.5 hours total testing process
  • Simply add treated blood sample and an off-board reagent to the Xpert cartridge

Robust Design

  • Includes two internal controls
  • 4 mL input volume of whole blood supports high assay sensitivity for detection of low-level transcripts
     

The Impact


  • Clinical Researcher: Same day information
  • Laboratory: Flexibility and simplicity for a more streamlined workflow 

Move your lab forward

  • Decrease costs: Eliminate need for standard curve and replicate testing
  • Optimize lab organization: Free up technician time for other lab services
  • Provide Flexibilty: Process any number of samples, any day of the week, with a fixed cost per sample
  • Simplify Reporting: Deliver information on concise one-page report

Ordering Info


Xpert® NPM1 Mutation  

Number of Tests: 10

Catalog #: RNPM1-10
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