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Xpert ® HIV-1 Viral Load XC

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HIV-1 computer generated depiction.

Badania molekularne następnej generacji do monitorowania wiremii i zakażenia wirusem HIV-1

Potrzeba

An ill woman listens to a physician.
  • Measurement of blood plasma HIV-1 RNA using PCR is established as the standard of care in assessing HIV-positive patient prognosis and response to antiretroviral therapy
  • It is estimated that only 75% of people living with HIV worldwide have access to viral load testing. In Low and Middle-Income Countries (LMICs), this figure is below 50%1
  • HIV viral load tests that can be deployed beyond centralized laboratories are needed to expand access to the standard of care.1
1 Malisa et al 2023 Nature Scientifc Reports | (2023) 13:4578 | https://doi.org/10.1038/s41598-023-31103-y

Rozwiązanie

A male and a female researchers scanning cepheid test cartridges.
  • The Xpert HIV-1 Viral Load XC test is an on-demand quantitative PCR test incorporating dual target detection for extended strain coverage
  • Using GeneXpert® technology, the Xpert HIV-1 Viral Load XC test automates the test process in one fully integrated cartridge and enables testing in laboratory or near‑patient testing environments
  • Provides users with advantages of simple workflow, fast results, and flexibility for low-to-high volume testing
Xpert® HIV‑1 Viral Load XC is intended to be performed by trained professional users or trained healthcare workers in laboratory or near-patient testing environments.

Wpływ

A smiling female doctor attends an elderly woman.
  • Lepsza opieka nad pacjentem: Enable better treatment options by reduced loss to follow-up and shorter turn-around times between sample collection and reporting results to patients2
  • Większa skuteczność: Fast results enable earlier interventions with counseling and therapy2.3
  • Increase access to viral load testing: Deliver lab-quality results in multiple settings3.4
2 Drain, Paul K et al. “Point-of-care HIV viral load testing combined with task shifting to improve treatment outcomes (STREAM): findings from an open-label, non-inferiority, randomised controlled trial.” The Lancet. HIV vol. 7.4 (2020): e229-e237. doi:10.1016/S2352-3018(19)30402-3
3 Jienchi et al .2022 Oct 1;91(2):189-196. doi: 10.1097/QAI.0000000000003037. Epub 2022 Jun 13
4 Ehret et al, 2022, J Clin Vir. Performance assessment of the new Xpert® HIV-1 viral load XC assay for quantification of HIV-1 viral loads, https://doi.org/10.1016/j.jcv.2022.105127

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