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Xpert® Xpress Strep A

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streptococus computer generated depiction.

Delivers accurate and timely results that optimize fast treatment decisions

The Need

an ill woman listens to a physician
To accurately diagnose pharyngitis caused by Group A Streptococcus (GAS) due to increasing incidence and prevalence globally.
  • Annually, 616 million people have GAS pharyngitis, more than 18.1 million people develop severe GAS disease and more than 517,000 people die due to severe GAS disease.1
Reduce overuse of antibiotics for the treatment of pharyngitis
  • Literature shows 37% of children who presented with pharyngitis tested positive for GAS, however 56% of visits were associated with antibiotic prescriptions. Similarly, 18% of adults presented with pharyngitis caused by GAS, but 72% were treated with antibiotics.2
(1) The Global Burden of Group A Streptococcal Diseases. Lancet Infect Dis. 2005 Nov; 5(11):685-94.
(2) Fleming-Dutra KE, et al. Prevalence of Inappropriate Antibiotic Prescriptions Among US Ambulatory Care Visits, 2010-2011. JAMA. 2016 May 3;315(17):1864-73.;
(3) Workflow studies conducted by Cepheid Solutions demonstrate that a throat culture confirmation workup costs~ $9.13 per culture. (Average cost includes reagents, labor cost and time). Data on file.
(4) Shulman ST, et al. Clinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 Update by the Infectious Diseases Society of America. Clin Infect Dis. 2012 Nov 15;55(10):1279-82.

The Solution

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  • Cepheid provides on-demand testing for Group A Strep in as soon as 18 minutes.*
  • Careful selection of the target gene.
  • Delivers timely results to support clinical decision-making.
* Full test runtime is 24 minutes. Positive results available in as soon as 18 minutes with early assay termination.

The Impact

a smiling female doctor attends an elderly woman
  • Accurate diagnosis of GAS supports antimicrobial stewardship initiatives and may reduce the amount of patients inappropriately prescribed antibiotics.
  • May support testing efficiency and potential cost savings by reducing follow‑up culture testing in certain settings.3
  • In clinical practice, treating an infected person with an appropriate antibiotic generally prevents the spread of infection and reduces the risk of post‑infectious complications, such as rheumatic fever and acute glomerular nephritis.
(3) Workflow studies conducted by Cepheid Solutions demonstrate that a throat culture confirmation workup costs~ $9.13 per culture. (Average cost includes reagents, labor cost and time). Data on file.

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