Xpert® MRSA/SA Blood Culture

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Xpert® MRSA/SA BC (Kit da 10 test)

GXMRSA/SABC-CE-10

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Domande frequenti

1. What is the Xpert® MRSA/SA Blood Culture test?

1. What is the Xpert® MRSA/SA Blood Culture test?

The Xpert® MRSA/SA Blood Culture test, performed on the GeneXpert® systems, is a qualitative in vitro diagnostic test intended for the detection of Staphylococcus aureus (SA) and methicillin-resistant Staphylococcus aureus (MRSA) DNA directly from positive blood cultures.1

2. How does the Xpert® MRSA/SA Blood Culture test work?

2. How does the Xpert® MRSA/SA Blood Culture test work?

The test utilizes automated real-time polymerase chain reaction (PCR) to detect MRSA/SA DNA.1

3. What is the indicated use for the Xpert MRSA/SA Blood Culture test?

3. What is the indicated use for the Xpert MRSA/SA Blood Culture test?

The Xpert MRSA/SA Blood Culture test is indicated for use in conjunction with other laboratory tests, such as culture, and clinical data available to the clinician as an aid in the detection of MRSA/SA from positive blood cultures. Subculturing of positive blood cultures is necessary to recover organisms for susceptibility testing or for epidemiological typing. The Cepheid Xpert MRSA/SA Blood Culture test is not intended to monitor treatment for MRSA/SA infections.1

4. What is Staphylococcus aureus (SA) and MRSA?

4. What is Staphylococcus aureus (SA) and MRSA?

Staphylococcus aureus (SA)  is a major nosocomial pathogen that causes a range of diseases including endocarditis, osteomyelitis, toxic shock syndrome, food poisoning, carbuncles and boils.1

In the early 1950s, acquisition and spread of beta-lactamase-producing plasmids thwarted the effectiveness of penicillin for treating SA infections. In 1959, methicillin, a semi-synthetic penicillin, was introduced and, soon after, methicillin-resistant SA (MRSA) strains were identified.1

Riferimenti bibliografici:

 

1. Xpert® MRSA/SA Blood Culture Package Insert.

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