You are using an unsupported browser.
Some features of this site may not function properly. For optimal user experience, please view this site in Chrome, Firefox, Safari, or Edge.

SARS-CoV-2

Test Information
Home / Tests / Sexual Health / RPMG FleX

ResistancePlus® MG FleXible*

M. genitalium + macrolide resistance detection

<em>ResistancePlus</em><sup>®</sup> MG FleXible*

The Need


M. genitalium is a recognised Sexually Transmitted Infection (STI), treated syndromically, with clinical presentation similar to that of Chlamydia trachomatis.1

Prevalence of M. genitalium infections in the general population ranges from 1-4%2, and its treatment is challenging due to high levels of macrolide resistance.5

  • Macrolide resistance testing is recommended by international and local guidelines on management of M. genitalium infections.3,4,6-8
  • Macrolide resistance testing can guide appropriate treatment choice enabling Resistance Guided Therapy.6
  • Resistance Guided Therapy is clinically demonstrated to improve patient cure rate and overall patient management.9
  • Fast detection of macrolide resistance can reduce time to cure, preventing ongoing transmission.9

The Solution


  • ResistancePlus® MG FleXible detects both M. genitalium and macrolide resistance in ~ 2 hours.
  • ResistancePlus® MG FleXible offers a fast and simple solution in combination with GeneXpert®Systems. Easily implemented into your existing workflow or setting, with minimal preparation time ~ 10 mins.
  • High performance test validates a wide range of specimen types and collection devices, including urine and swabs (vaginal, cervical, rectal).**

The Impact


Improving patient management

ResistancePlus® MG FleXible provides therapeutic guidance recommendations, enabling clinicians to make informed treatment decisions. Resistance guided therapy is clinically demonstrated to increase overall patient cure rate.9

ResistancePlus® MG FleXible is validated on a wide range of sample types including rectal, male and female urine, and common collection swab kits including Xpert® CT/NGVaginal/Endocervical Specimen Collection kit and Xpert® CT/NG Urine Specimen Collection Kit.**

CE-IVD in Vitro Diagnostic Medical Device. Not available in all countries.
*Exclusively distributed by Cepheid under the FleXible by GeneXpert® System program
**Validated specimens: male and female urine, vaginal swab, cervical swab, rectal swab, urethral swab, from symptomatic and asymptomatic patients. Validated collection kits: Xpert® Vaginal/Endocervical and Xpert® Urine  Specimen Collection Kits, Neat urine, Regular FLOQSwab™ in 3 ml of UTM™  media, cobas PCR collection media. For details refer to the ResistancePlus® MG FleXible Instructions For Use (IF-IV0012)
SWAB-G-50

1. Manhart LE and Kay N.Mycoplasma genitalium: Is It a Sexually Transmitted Pathogen? Curr. Infect. Dis. Reps. 2010; 12(4):306-313.
2. Cools et al,  Lancet Infectious DiseasesVol. 20No. 11p1222–1223
3. 2018 BASHH UK national guideline for the management of infection withMycoplasma genitalium. Available online at https://www.bashhguidelines.org/media/1198/mg-2018.pdf
4. Jensen et al. 2016 European guideline onMycoplasma genitalium infections.  J Eur Acad Dermatol Venereol. 2016 Oct;30(10):1650-1656.
5. Unemo, M et al. Antimicrobial-resistant sexually transmitted infections: gonorrhoea andMycoplasma genitalium. Nat Rev Urol. 2017 Mar;14(3):139-152.
6. Horner PJ et al. 2016 European guideline on the management of non-gonococcal urethritis.  Int J STD AIDS. 2016 Oct;27(11):928-37.
7. Australian STI Management Guidelines – Mycoplasma genitalium 2018. http://www.sti.guidelines.org.au/sexually-transmissible-infections/mycoplasma-genitalium
8. Groupe Infectiologie Dermatologique et Infections Sexuellement GRIDIST and Société Fançaise de Dermatologie – Press Release. Available online at: https://www.sfdermato.org/actualites/communique-commun-gridist-et-sfd.html
9. Read TRH et al. Outcomes of Resistance-guided Sequential Treatment of Mycoplasma genitalium Infections: A Prospective Evaluation.  Clin Infect Dis. 2019 Feb 1;68(4):554-560.

ResistancePlus® MG FleXible tests are developed and manufactured by SpeeDx Pty Ltd, Sydney. PlexPCR® & ResistancePlus® are trademarks of SpeeDx Pty Ltd. Other copyright and trademarks are the property of the respective owners. SpeeDx Pty Ltd products may be covered by one or more local or foreign patents. Visit www.plexpcr.com/patents for comprehensive patent information

Ordering Info


ResistancePlus® MG FleXible

10 tests

Catalog #: S2A-2000410

ResistancePlus®MG S2A Positive Control

10 tests

Catalog #: S2A-95004

Kits

Xpert Vaginal/Endocervical Specimen Collection kits – 50 ready-to-use individual kits

Catalog #: SWAB/A-50, SWAB/G-50

Kits

50 Ready-To-Use Individual Kits

Catalog #: URINE/A-50
Back to Top