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Four Core Actions to Fight Infections & Antimicrobial Resistance

1

Preventing the Spread

2

Tracking Resistant Bacteria

3

Improving Antibiotic Prescribing and Stewardship

4

Developing Advanced Diagnostics & New Antibiotics

Impact of Rapid Diagnostics

Shortened hospital length of stay by 2.5 days3

Decreased lethal bloodstream infections in patients by 36%3

Reduced time to effective therapy by 5 hours3

Impact Briefs

Ephraim McDowell Regional Medical Center improves adherence to optimized testing protocols for C. difficile resulting in lower C. difficile rates and decreased patient time in isolation.


The Federation of Infection Societies Annual Conference at the International Convention Centre in Birmingham was the venue for the symposium Fighting the challenge of CPE, which took a look at one hospital’s approach to addressing the challenges posed by carbapenamase-producing Enterobacteriaceae (CPE).


Mercy Health Saint Mary’s in Grand Rapids, MI reduces time to result and improves treatment accuracy through the use of Xpert® CT/NG and antimicrobial stewardship interventions.


Millard Henry Clinic (MHC) improves treatment accuracy through the use of Xpert® Xpress Flu/RSV and antimicrobial stewardship interventions while maintaining efficient patient flow during a very busy flu season.


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1.Casari E, et al. Reducing rates of Clostridium difficile infection by switching to a stand-alone NAAT with clear sampling criteria. Antimicrob Resist Infect Control. 2018;7:40.

2.Birgand G, et al. Rapid detection of glycopeptide-resistant enterococci: impact on decision-making and costs. Antimicrob Resist Infect Control. 2013 Nov 4;2(1):30.

3.Wenzler E, Using rapid diagnostics to fight resistance. Infectious Disease Special Edition. May 30, 2018. https://www.idse.net/Resistance--Stewardship/Article/09-15/Using-Rapid-
Diagnostics-to-Fight-Resistance/48730. Accessed 12 July 2018

4.Bauer KA, et al. An Antimicrobial Stewardship Program’s Impact with Rapid olymerase chain reaction methicillin-resistant/ Staphylococcus Blood Culture Test in Patients with Staphylococcus Bacteremia. ClinInfect Dis. 2010; 51(9):1074–1080.

5.Humphreys H, et al. Staphylococcus and surgical site infections: benefits of screening and decolonization before surgery. J Hosp Infect. 2016. Nov;94(3):295-304.

6.Rudd K, et al. Molecular Diagnostics Can Lead To Early Optimization of Antimicrobial Therapy for Staphylococcal Bacteremia: Experience at a Large Tertiary-Care VA Medical Center. Open Forum Infectious Diseases, Volume 3, Issue suppl_1, 1 December 2016, 1863. Accessed 12 July 2018.

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