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Xpert® Xpress CoV-2 plus

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Collection devices

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Copan 305CN (Nasopharyngeal Swab) (Pack of 50)

305C

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Copan 346N (Nasal Swab) (Pack of 50)

346C

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FAQs

1. How is the Xpert® Xpress CoV-2 plus product different from the existing Xpert® Xpress SARS-CoV-2 product?

1. How is the Xpert® Xpress CoV-2 plus product different from the existing Xpert® Xpress SARS-CoV-2 product?

Cepheid developed the Xpert® Xpress CoV-2 plus test with several enhancements compared to the Xpert® Xpress SARS-CoV-2.  Key enhancements include:

    • The addition of a 3rd gene target for SARS-CoV-2 (RdRP now included in addition to E and N2), to be more robust against mutations

    • Improved Time to Result (TTR) at about 30 minutes

    • Expansion of on-label transport media options to include the addition of eNAT®

2. What sample types and collection devices can be used with Xpert® Xpress CoV-2 plus?

2. What sample types and collection devices can be used with Xpert® Xpress CoV-2 plus?

Sample Types:

GeneXpert Dx and Infinity Systems: Nasopharyngeal swab and anterior nasal swab in 3mL of viral transport media (UTM/VTM), 3mL of Saline, or 2mL of eNAT, from individuals meeting COVID-19 clinical and/or epidemiological criteria, as well as individuals without symptoms or other reasons to suspect COVID-19 infection.

3. What are my options for Viral Transport Media for Xpert® Xpress CoV-2 plus?

3. What are my options for Viral Transport Media for Xpert® Xpress CoV-2 plus?

Viral transport media are available from several commercial vendors who may use the terminology VTM (Viral Transport Medium) or UTM (Universal Transport Medium). Any brand meeting the guidelines for VTM/UTM can be used. UTM, VTM, Saline, and eNAT are on label.

4. What external quality control (QC) material options are available for Xpert® Xpress CoV-2 plus? The listed external controls are Zeptometrix External Controls:

4. What external quality control (QC) material options are available for Xpert® Xpress CoV-2 plus? The listed external controls are Zeptometrix External Controls:

    • SARS-Related Coronavirus 2 (SARS-CoV-2) External Run Control, Catalog# NATSARS(COV2)-ERC

    • SARS Associated Coronavirus 2 (SARS-CoV-2) Negative Control, Catalog# NATSARS(COV2)-NEG

These are described in the “materials available but not provided” section of the package insert as the recommended source for external controls. Please consult with Cepheid’s Technical Support team to inquire about other commercial sources for QC material. 

5. What are my options for obtaining the ADF or the Package Insert for my Xpert® Xpress CoV-2 plus test?

5. What are my options for obtaining the ADF or the Package Insert for my Xpert® Xpress CoV-2 plus test?

In an effort to reduce our environmental footprint, Cepheid is moving towards CD-less products.  The Package Inserts, ADFs and ADF import instructions for the Xpert® Xpress CoV-2 plus test are available for download on this website (see above).  For customers who prefer to obtain the ADFs in a CD, please fill out the CD ADF request using the following link:

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