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Xpert® Bladder Cancer Detection

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Bladder cancer computer generated depiction.

Détection de la présence du cancer de la vessie chez des patients présentant une hématurie en 90 minutes environ

Le besoin

An ill woman listens to a physician.
Early and accurate diagnosis of bladder cancer is critical in patients with hematuria.3
  • Four out of five people with bladder cancer have blood in their urine4
  • But 80–90% of patients with visible hematuria, and over 95% of patients with non-visible hematuria do NOT have cancer
  • There are many known causes of hematuria including urinary tract infection, nephrolitiasis (stones), etc4
  • In patients with hematuria, it can be difficult to decide which patients might have cancer and which patients might have a different condition
  • Primary care physicians are sometimes reluctant to refer patients with visible or significant microscopic hematuria to urology for further investigation5
3 Kamat AM, et al. Bladder Cancer. Lancet. 2016 Dec 3;388(10061):2796-2810.
4 Avellino G, et al. Diagnosis and Management of hematuria. Surg Clin North Am. 2016 Jun;96(3): 503-15.
5 Yafi FA, et al. Patients with microscopic and gross hematuria: practice and referral patterns among primary care physicians in a universal health care system. Can Urol Assoc J 2011;5(2):97-101.

La solution

A male and a female researchers scanning cepheid test cartridges.
Xpert Bladder Cancer Detection is a non-invasive biomarker test for patients with hematuria that is used in conjunction with other clinical measures.
  • Five mRNA biomarkers were validated for the detection of bladder cancer
  • The non-invasive and painless test uses voided urine samples
  • The test is performed using a self-contained cartridge and system, and can be performed in any size urology lab
  • Each cartridge contains three controls for dependable results
  • Sample stability for up to 7 days in Xpert® Urine Transport Reagent
  • The test supports on‑demand testing

L’impact

A smiling female doctor attends an elderly woman.
A test that helps clinicians gain information for patients with hematuria.
  • Non‑invasive urine‑based testing may help avoid the discomfort associated with invasive procedures6
  • A high negative predictive value provides additional information to support clinical assessment.
  • Easy to implement and train
  • A cartridge‑based" test and workflow with decentralized laboratory testing
6 Biardeau X, et al. Prospective evaluation of anxiety, pain, and embarrassment associated with cystoscopy and urodynamic testing in clinical practice. Can Urol Assoc J. 2017 Mar-Apr; 11(3-4): 104–110.

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