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Xpert® HBV Viral Load

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HBV Viral Load computer generated depiction.

Quantitation of Hepatitis B Virus (HBV) in less than one hour

The Need

An ill woman listens to a physician.
  • Although a vaccine for HBV exists, there is still no cure and lifelong treatment is needed for individuals already chronically infected with Hepatitis B Virus
  • HBV rapid antibody testing is mainly done at point of care or in community based programmes but HBV viral load testing and monitoring is traditionally done in the laboratory with long turnaround times, which can result in more patients being lost to follow up and care3,4
3 Gupta et al. 2021. Performance evaluation of Xpert HBV viral load (VL) assay: Point-of-care molecular test to strengthen and decentralize management of chronic hepatitis B (CHB) infection J of Virol Methods https://doi.org/10.1016/j.jviromet.2021.114063
4 Woldemedihn et al., 2021 Validity of a point-of-care viral load test for hepatitis B in a low-income setting. J Virol Methods https://doi.org/10.1016/j.jviromet.2021.114063

The Solution

A male and a female researchers scanning cepheid test cartridges.
  • The Xpert HBV Viral Load (VL) test is an in vitro nucleic acid amplification test designed for the quantitation of Hepatitis B Virus DNA in human serum or plasma (EDTA) from chronically HBV-infected individuals.
  • Disease management could be simplified with accurate quantification of HBV DNA, flexible test thoughput and on-demand results available in 1 hour.

The Impact

A smiling female doctor attends an elderly woman.
  • Improve Patient Care: Same-day results support better clinical decisions 3
  • Increase Efficiency: Accurate, on-demand results in 60 minutes with minimal hands-on time improves efficiency 1,2
  • Patient Centered Diagnostics: Simple workflow enables testing closer to patients 3,4
1 Abranavel et al., 2019. Diagnostic Microbiology and Infectious Disease. Diagnostic Microbiology and infect Disease. https://doi.org/10.1016/j.diagmicrobio.2019.114946 2 Marcuccilli et al., 2021. Multicenter Evaluations of Cepheid Xpert HBV Viral Load test https://doi.org/10.3390/diagnostics11020297 3 Gupta et al. 2021. Performance evaluation of Xpert HBV viral load (VL) assay: Point-of-care molecular test to strengthen and decentralize management of chronic hepatitis B (CHB) infection J of Virol Methods https://doi.org/10.1016/j.jviromet.2021.114063 4 Woldemedihn et al., 2021 Validity of a point-of-care viral load test for hepatitis B in a low-income setting. J Virol Methods https://doi.org/10.1016/j.jviromet.2021.114063

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