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Xpert® MRSA NxG (10-test kit)
GXMRSA-NXG-10
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Collection devices
Collection Device (Pack of 50)
900-0370
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Package Insert
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Package Insert
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MSDS/SDS
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GXVANA-10
Rapid VRE screening for active outbreak prevention and control in around 48 minutes
GXNOV-10
Fast detection of Norovirus GI & GII with results available in 90 minutes
GXSACOMP-10
Detection of S. aureus and MRSA in about 65 minutes
1. What is Xpert® MRSA NxG test intended for?
1. What is Xpert® MRSA NxG test intended for?
Xpert MRSA NxG is a qualitative in vitro diagnostic test intended for the detection of methicillin-resistant Staphylococcus aureus (MRSA) DNA directly from nasal swabs in patients at risk for nasal colonization.1
2. How is the Xpert® MRSA NxG test performed?
2. How is the Xpert® MRSA NxG test performed?
Xpert® MRSA NxG utilizes automated real-time polymerase chain reaction (PCR) for the amplification of MRSA specific DNA targets and fluorogenic target-specific hybridization probes for the real-time detection of the amplified DNA. The Xpert MRSA NxG test is intended to aid in the prevention and control of MRSA infections in healthcare settings. 1
3. Is the Xpert MRSA NxG test intended to diagnose MRSA infections?
3. Is the Xpert MRSA NxG test intended to diagnose MRSA infections?
The Xpert MRSA NxG test is not intended to diagnose, guide, or monitor treatment for MRSA infections, or provide results of susceptibility to methicillin. A negative result does not preclude MRSA nasal colonization. Concomitant cultures are necessary to recover organisms for epidemiological typing or for further susceptibility testing. 1
4. What is Staphylococcus aureus (SA) and MRSA?
4. What is Staphylococcus aureus (SA) and MRSA?
Staphylococcus aureus (SA) is a human pathogen, which is the causative agent of a range of diseases including bacteremia, endocarditis, osteomyelitis, toxic shock syndrome, food poisoning, carbuncles, and boils.1
In the early 1950s, acquisition and spread of beta-lactamase-producing plasmids thwarted the effectiveness of penicillin for treating SA infections. In 1959, methicillin, a semi-synthetic penicillin, was introduced and, soon after, methicillin-resistant SA (MRSA) strains were identified.1
5. How does being colonized with MRSA impact the likelihood of developing MRSA infections?
5. How does being colonized with MRSA impact the likelihood of developing MRSA infections?
MRSA colonization increases the risk of infection, with infecting strains match colonizing strains in as many as 50–80% of cases. MRSA nasal colonization rates range from 0.9% to 1.5% in the United States2
References:
1. Xpert® MRSA NxG Package Insert.
2. Turner, N.A., Sharma-Kuinkel, B.K., Maskarinec, S.A. et al. Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research. Nat Rev Microbiol 17, 203–218 (2019). https://doi.org/10.1038/s41579-018-0147-4
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