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Xpert Xpress SARS-CoV-2 Test
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Xpert® EV

Xpert EVA molecular in vitro diagnostic Enteroviral meningitis test

Ordering Info

"Knowing whether the meningitis is viral or bacterial is imperative to early effective treatment. Because Xpert EV is significantly faster than existing methods for diagnosing meningitis, it could minimize delays in treating patients. Swift recognition of the cause and appropriate treatment is critical to patient recovery.”

-Adopted from FDA News, P07-46, March 16, 2007

The Need

Enterovirus (EV) meningitis is very common among young children, but very difficult to differentiate from bacterial meningitis due to similar clinical presentations. As a result, patients are often admitted and treated empirically.

  • EV meningitis is estimated to cause 30,000 to 50,000 hospitalizations annually in the US
  • EV meningitis is usually self-limiting and does not require antibiotic treatment
  • EV meningitis and bacterial meningitis are very difficult to differentiate by symptoms alone
  • Suspected meningitis patients are often admitted and treated empirically
  • Empirical treatment of suspected meningitis patients are costly for hospitals
(1) Viral (Aseptic) Meningitis. Centers for Disease Control and Prevention: Respiratory and Enteric Viruses Branch. (15 October 2004).; (2) HA. Viral meningitis. Semin Neurol. 2000; 20(3): 277-92.; (3) Romero JR, Rotbart HA. Enteroviruses. In: Murray PR, Baron EJ, eds. Manual of Clinical Microbiology. 8th edition. Washington, DC: American Society for Microbiology, 2003: 1427-1438.; (4) Robinson CC, Willis M, Meagher A, et al. Impact of rapid polymerase chain reaction results on management of pediatric patients with enteroviral meningitis. Pediatric Infectious Disease Journal. 2002; 21: 283-6.; (5) Cost Savings Through Rapid Diagnosis of Enteroviral Menengitis. Pediatric Infectious Disease Journal. 2004; (6) Ramers C, Billman G, Hartin M, Ho S, Sawyer M. Impact of a Diagnostic Cerebrospinal Fluid Enterovirus Polymerase Chain Reaction Test on Patient Management. IAMA. 2000; 283, 20

The Solution

Rapid and accurate detection of enterovirus from the Central Spinal Fluid (CSF) specimen enables establishment of an effective patient management pathway.

  • Rapid and accurate EV result in about 2.5 hours is clinically actionable
  • Physicians can confidently identify patients with EV meninigitis and manage them appropriately instead of empirical treatment
  • Timely answers provide assurance to patients and their families to reduce anxiety

The Impact

The impact of Cepheid's Xpert EV is substantial: Identifying those patients with Enterovirus and helping to rule out bacterial meningitis quickly allows for appropriate management of patients. Timely answers provides assurance to patients and their families which helps to reduce anxiety.

Ordering Info

Xpert® EV

Number of Tests: 10

Catalog #: GXEV-100N-10
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