Cepheid GeneXpert 10-Color Multiplexing Technology
10-Color technology combined with PCR followed by melt curve analysis
GeneXpert Systems with 10-Color Technology Deliver:
By using probes labeled with different fluorescent reporter dyes, numerous targets can be detected simultaneously in a single reaction tube. Since four more fluorescent channels are now available, the number of possible targets increases, allowing for more complex assay designs. Each target can be independently monitored by the innovative excitation-emission system in the Cepheid GeneXpert System with 10-Color technology.
With this increased testing power we can detect a wide range of bacteria and viruses, as well as fungi with one test. Additionally, this technology also makes it possible to identify multiple antimicrobial resistance markers from one sample.
For example, with the first Cepheid 10-Color test, Xpert® MTB/XDR#, the 10-Color module significantly increases the assay multiplexing capacity, which in turn expands the number of antimicrobial resistance genes that can be detected.
The new 10-Color assay targets as many as eight genes for detection of M. tuberculosis and resistance to as many as six drugs: isoniazid, fluoroquinolones, amikacin, kanamycin, capreomycin and ethionamide.
A new era of high-level multiplexing real-time PCR instruments will revolutionize molecular diagnostics with:
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